A1BG polyclonal Antibody | BS5591

A1BG polyclonal Antibody | BS5591 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: A1BG (α-1B-glycoprotein), also known as A1B, ABG, GAB or HYST2477, is a 495 amino acid secreted glycoprotein that contains five immunoglobulin (Ig) -like V-type domains and belongs to the immunoglobulin superfamily. At an average concentration of 22mg/dl, A1BG is expressed in normal adult plasma and is thought to be involved in the regulation of cell behavior and cell recognition. In plasma, A1BG specifically binds to human CRISP-3, a member of the cysteine-rich secretory protein (CRISP) family comprised of evolutionarily conserved proteins which are believed to play a role in the innate immune system. Through its association with CRISP-3, A1BG is believed to function in protecting the body from the circulation of free CRISP-3, a circumstance with potentially harmful effects.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: A1BG polyclonal Antibody detects endogenous levels of A1BG protein.

Molecular Weight: ~ 54 kDa, 68 kDa (deglycosylated)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Alpha-1B-glycoprotein; Alpha-1-B glycoprotein; α-1B-glycoprotein; α1B-glycoprotein; α-1-B-glycoprotein

Immunogen: Synthetic peptide, corresponding to amino acids 182-227 of Human A1BG.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: NF-kB Signaling,