AADAC Polyclonal Antibody | E-AB-10690

AADAC Polyclonal Antibody | E-AB-10690 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: AAAD, Aada, Aadac, Arylacetamide deacetylase (esterase), Arylacetamide deacetylase, CES5A1, DAC

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Metabolism, Signal Transduction

Background: Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens. Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionally causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores.

Concentration: 0.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human AADAC

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 46 kDa

Molecular Weight(Observed): N/A