AARS2 Polyclonal Antibody | E-AB-10116

AARS2 Polyclonal Antibody | E-AB-10116 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: AARS 2, AARS2, AARSL, Alanine tRNA ligase 2 mitochondrial, Alanine tRNA ligase, Alanyl tRNA synthetase 2 mitochondrial, Alanyl tRNA synthetase like, AlaRS, bA444E17.1, COXPD8, Gm89, KIAA1270, LKENP, MGC69820, MT ALARS, MTALARS, Probable alanyl tRNA synthetase mitochondrial, RP11-444E17.1

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling

Background: The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human AARS2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 107 kDa

Molecular Weight(Observed): N/A