ABCG2 Polyclonal Antibody | E-AB-30393

ABCG2 Polyclonal Antibody | E-AB-30393 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ABC transporter, ABC15, ABCG 2, ABCG2, ABCG2, ABCP, ATP binding cassette sub family G (WHITE) member 2, ATP binding cassette transporter G2, ATP-binding cassette sub-family G member 2, BCRP, BCRP1, BMDP, Breast cancer resistance protein, CD338, CDw338, CDw338 antigen, EST157481, GOUT1, MGC102821, Mitoxantrone resistance associated protein, Mitoxantrone resistance-associated protein, MRX, Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2, MXR, MXR1, Placenta specific ATP binding cassette transporter, Placenta specific MDR protein, Placenta-specific ATP-binding cassette transporter, UAQTL1

Application: WB, IHC-p, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Signal Transduction, Stem Cells, Tags and Cell Markers

Background: Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from the Internal region of human ABCG2.

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 72 kDa

Molecular Weight(Observed): 72 kDa