ABI2 Polyclonal Antibody | E-AB-18253

ABI2 Polyclonal Antibody | E-AB-18253 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Abelson interactor 2, ABI 2, Abi-2, ABI2, ABI2, ABI2B, Abl binding protein 3, Abl interacting protein 1 (SH3 containing protein), Abl interactor 2, Abl interactor protein 2b, Abl-binding protein 3, AblBP3, AIP 1, Arg binding protein 1, Arg protein tyrosine kinase binding protein, Arg-binding protein 1, ArgBP1, ARGBPIA, ArgBPIB, OTTHUMP00000163783, OTTHUMP00000163784, OTTHUMP00000206182, OTTHUMP00000206183, OTTHUMP00000206184, OTTHUMP00000206185, SSH3BP2

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer

Background: May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.

Concentration: 0.78 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human ABI2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A