Abiraterone | B1607

Abiraterone (CB-7598) is a potent steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase (CYP17) inhibitor with an IC50 at 4 nM

Abiraterone (CB-7598) is a potent steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase (CYP17) inhibitor with an IC50 at 4 nM

B1607 | Abiraterone DataSheet

Alternate Name/Synonyms: CYP17 inhibitor, CB-7598, CB 7598, CB7598 (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-pyridin-3-yl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol

Appearance: Solid

Formulation: N/A

CAS Number: 154229-19-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₄H₃₁NO

Molecular Weight: 349.51

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO: < 1 mg/ml; H2O: < 1 mg/ml

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase (CYP17) inhibitor with an IC50 at 4 nM

MDL Number: MFCD00924100

PubChem CID: 132971

SMILES: CC12CCC(CC1=CCC3C2CCC4(C3CC=C4C5=CN=CC=C5)C)O

InChi: 1S/C24H31NO/c1-23-11-9-18(26)14-17(23)5-6-19-21-8-7-20(16-4-3-13-25-15-16)24(21,2)12-10-22(19)23/h3-5,7,13,15,18-19,21-22,26H,6,8-12,14H2,1-2H3/t18-,19-,21-,22-,23-,24+/m0/s1

InChi Key: GZOSMCIZMLWJML-VJLLXTKPSA-N