AC710 | 2884

AC710 is a potent, and selective PDGFR-family kinases inhibitor with Kd values of 0.6 nM,1.0 nM, 1.3 nM and 1.0 nM for FLT3, KIT, PDGFRα and PDGFRβ respectively. Displays potent anticancer activity.

AC710 is a potent, and selective PDGFR-family kinases inhibitor with Kd values of 0.6 nM,1.0 nM, 1.3 nM and 1.0 nM for FLT3, KIT, PDGFRα and PDGFRβ respectively. Displays potent anticancer activity.

2884 | AC710 DataSheet

Alternate Name/Synonyms: N-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-5-((1-ethyl-2,2,6,6-tetramethylpiperidin-4-yl)oxy)picolinamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1351522-04-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₁H₄₂N₆O₄

Molecular Weight: 562.7

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent PDGFR-family kinases inhibitor

MDL Number: N/A

PubChem CID: 54760053

SMILES: CCN1C(CC(CC1(C)C)OC2=CN=C(C=C2)C(=O)NC3=CC=C(C=C3)NC(=O)NC4=NOC(=C4)C(C)(C)C)(C)C

InChi: InChI=1S/C31H42N6O4/c1-9-37-30(5,6)17-23(18-31(37,7)8)40-22-14-15-24(32-19-22)27(38)33-20-10-12-21(13-11-20)34-28(39)35-26-16-25(41-36-26)29(2,3)4/h10-16,19,23H,9,17-18H2,1-8H3,(H,33,38)(H2,34,35,36,39)

InChi Key: JVCWPUFNLFSKFS-UHFFFAOYSA-N