Acarbose | B2104

Acarbose is an inhibitor of α-glucosidase and pancreatic α-amylase with antihyperglycemic activity. Acarbose binds to and inhibits α-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. Acarbose has been used to inhibit postprandial hyperglycemia associated with diabetes without cardiovascular complications.

Acarbose is an inhibitor of α-glucosidase and pancreatic α-amylase with antihyperglycemic activity. Acarbose binds to and inhibits α-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. Acarbose has been used to inhibit postprandial hyperglycemia associated with diabetes without cardiovascular complications.

B2104 | Acarbose DataSheet

Alternate Name/Synonyms: O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-D-glucose; BAY-g 5421

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 56180-94-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₅H₄₃NO₁₈

Molecular Weight: 645.6

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: H₂O (50 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: An inhibitor of α-glucosidase and a antidiabetic agent

MDL Number: MFCD00869592

PubChem CID: 41774

SMILES: CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)NC4C=C(C(C(C4O)O)O)CO

InChi: InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23?,24-,25-/m1/s1

InChi Key: XUFXOAAUWZOOIT-UGEKTDRHSA-N