ACE1 Polyclonal Antibody | E-AB-12223

ACE1 Polyclonal Antibody | E-AB-12223 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ACE 1, ACE, ACE T, ACE, ACE1, Angiotensin converting enzyme somatic isoform, Angiotensin converting enzyme testis specific isoform, Angiotensin I converting enzyme 1, Angiotensin I converting enzyme, Angiotensin I converting enzyme peptidyl dipeptidase A 1, angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript, Angiotensin-converting enzyme, Carboxycathepsin, CD 143, CD143, CD143 antigen, DCP 1, DCP, DCP1, Dipeptidyl carboxypeptidase 1, Dipeptidyl carboxypeptidase I, Kininase II, MGC26566, MVCD3, Peptidase P, Peptidyl dipeptidase A, soluble form, Testicular ECA

Application: WB, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction, Stem Cells

Background: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human ACE

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:5000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 150 kDa

Molecular Weight(Observed): N/A