ACE2 polyclonal antibody | NCP0035

ACE2 polyclonal antibody | NCP0035 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: COVID-19

Application: WB: 1:2000~10000

Background: The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2 (COVID-19 virus) .

Concentration: Rabbit IgG, 1 mg/ml in PBS with 0.02% sodium azide, 10% glycerol, pH7.2

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ACE2 pAb detects endogenous levels of S-RCD protein.

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Angiotensin I converting enzyme 2;Severe acute respiratory syndrome coronavirus 2; SARS-CoV-2; HCoV-19; SARS2; 2019-nCoV; COVID-19; COVID-19 virus; Human coronavirus 2019

Immunogen: recombinant protein