Acetyl Coenzyme A Carboxylase Polyclonal Antibody | BS65613

Acetyl Coenzyme A Carboxylase Polyclonal Antibody | BS65613 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Cow,Monkey,

Application: IHC-P

Application Range: IHC-P=1:100-500

Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Acetyl Coenzyme A Carboxylase Polyclonal Antibody detects endogenous levels of Acetyl Coenzyme A Carboxylase protein.

Molecular Weight: 265kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Acetyl Coenzyme A Carboxylase; ACAS2; AceCS; Acetate CoA ligase; Acetyl CoA synthetase; Acetyl coenzyme A synthetase cytoplasmic; Acetyl-CoA synthetase; ACS; ACSA; ACSS2; Acyl activating enzyme; Acyl CoA synthetase short chain family member 2; EC 6.2.1.1; MYH7B; ACAC; ACACB; ACC alpha; ACC beta; ACC1; ACC2; ACCA; ACCB; Acetyl CoA carboxylase 1; Acetyl CoA carboxylase 2; Acetyl CoA carboxylase alpha; Acetyl CoA carboxylase beta; Biotin carboxylase; COA1; COA2; HFA1; ACACB_HUMAN; ACACA_HUMAN; Acetyl Coenzyme A Carboxylase; Acetyl-CoA carboxylase 1; ACC1; ACC-alpha; Acetyl-CoA carboxylase 265; ACC-alpha; ACC-beta.

Immunogen: KLH conjugated synthetic peptide derived from human Acetyl Coenzyme A Carboxylase 1/2:2307-2355/2458

Conjugate: Unconjugated

Modification: Acetylated

Purification & Purity: affinity purified by Protein A

Pathway: