Acivicin | B1028

Acivicin is an antibiotic that inhibits γ-glutamyl transpeptidase (γ-GT), an enzyme involved in transferring g-glutamyl groups in the cell membranes of kidneys, heart, brain, and pancreas. Acivicin is a potent antitumor agent that induces apoptosis in human lymphoblastoid cells. Also displays antimicrobial activities.

Acivicin is an antibiotic that inhibits γ-glutamyl transpeptidase (γ-GT), an enzyme involved in transferring g-glutamyl groups in the cell membranes of kidneys, heart, brain, and pancreas. Acivicin is a potent antitumor agent that induces apoptosis in human lymphoblastoid cells. Also displays antimicrobial activities.

B1028 | Acivicin DataSheet

Alternate Name/Synonyms: (2S)-2-amino-2-[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]acetic acid; Antibiotic AT-125; NSC 163501; U42126

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 42228-92-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₅H₇ClN₂O₃

Molecular Weight: 178.57

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: H₂O (~10 mg/ml after warming)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: An antibiotic that inhibits γ-glutamyl transpeptidase (γ-GT)

MDL Number: MCFD00866432

PubChem CID: 294641

SMILES: C1C(ON=C1Cl)C(C(=O)O)N

InChi: InChI=1S/C5H7ClN2O3/c6-3-1-2(11-8-3)4(7)5(9)10/h2,4H,1,7H2,(H,9,10)/t2-,4-/m0/s1

InChi Key: QAWIHIJWNYOLBE-OKKQSCSOSA-N