Aclidinium bromide | B2281

Aclidinium bromide is a long-acting reversible antagonist at the muscarinic acetylcholine receptors (mAChRs), M1, M2, M3, M4, and M5 (Kis= 0.1, 0.14, 0.14, 0.21, and 0.16 nM, respectively). Useful for the treatment of chronic obstructive pulmonary disease

Aclidinium bromide is a long-acting reversible antagonist at the muscarinic acetylcholine receptors (mAChRs), M1, M2, M3, M4, and M5 (Kis= 0.1, 0.14, 0.14, 0.21, and 0.16 nM, respectively). Useful for the treatment of chronic obstructive pulmonary disease

B2281 | Aclidinium bromide DataSheet

Alternate Name/Synonyms: (3R)-3-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane, monobromide; LAS34273; LAS W-330

Appearance: Off-white solid

Formulation: N/A

CAS Number: 320345-99-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₆H₃₀NO₄S₂• Br

Molecular Weight: 564.6

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~15 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A long-acting reversible antagonist at the muscarinic acetylcholine receptors (mAChRs)

MDL Number: MFCD09954105

PubChem CID: 11519741

SMILES: C1C[N+]2(CCC1C(C2)OC(=O)C(C3=CC=CS3)(C4=CC=CS4)O)CCCOC5=CC=CC=C5.[Br-]

InChi: InChI=1S/C26H30NO4S2.BrH/c28-25(26(29,23-9-4-17-32-23)24-10-5-18-33-24)31-22-19-27(14-11-20(22)12-15-27)13-6-16-30-21-7-2-1-3-8-21;/h1-5,7-10,17-18,20,22,29H,6,11-16,19H2;1H/q+1;/p-1/t20?,22-,27?;/m0./s1

InChi Key: XLAKJQPTOJHYDR-QTQXQZBYSA-M