ACMSD Polyclonal Antibody | E-AB-10712

ACMSD Polyclonal Antibody | E-AB-10712 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 2 amino 3 carboxymuconate 6 semialdehyde decarboxylase, 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, acmsd, ACMSD, Aminocarboxymuconate semialdehyde decarboxylase, Picolinate carboxylase

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Signal Transduction

Background: The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.

Concentration: 0.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human ACMSD

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 38 kDa

Molecular Weight(Observed): N/A