ACSL6 (D531) polyclonal Antibody | BS3140

ACSL6 (D531) polyclonal Antibody | BS3140 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: IHC

Application Range: IHC:1:50~1:200

Background: Acyl-CoA synthetases, also known as long-chain fatty-acid CoA synthases (FACL) or Palmitoyl-CoA ligases, include ACSL1-6, which are all single-pass membrane proteins localizing to the mitochondrion, microsome or peroxisome.ACSL proteins are important for synthesis of cellular lipids and for β-oxidation degradation. Specifically, ACSL proteins catalyze the activation of long-chain fatty acids to acyl-CoAs, which can be metabolized to form CO2, triacylglycerol (TAG), phospholipids (PL) and cholesteryl esters (CE) . ACSL6 has been shown to be an ETV6 fusion partner gene in a recurrent t (5;12) (q31;p13) translocation in a patient with refractory anemia with excess blasts (RAEB) with basophilia, a patient with acute myelogenous leukemia (AML) with eosinophilia, and a patient with acute eosinophilic leukemia (AEL) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ACSL6 (D531) polyclonal Antibody detects endogenous levels of ACSL6 protein.

Molecular Weight: ~ 78 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Long-chain-fatty-acid--CoA ligase 6; Long-chain acyl-CoA synthetase 6; LACS 6; ACSL6; ACS2; FACL6; KIAA0837; LACS5

Immunogen: Synthetic peptide, corresponding to amino acids 500-550 of Human ACSL6.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: