ACT-129968 | B2316

A potent and selective CRTh2 antagonist. CRTh2 is a G-protein-coupled receptor for prostaglandin D2 (PGD2), a key mediator in inflammatory disorders.

ACT-129968 is a potent and selective CRTh2 antagonist. CRTh2 is a G-protein-coupled receptor for prostaglandin D2 (PGD2), a key mediator in inflammatory disorders.

B2316 | ACT-129968 DataSheet

Alternate Name/Synonyms: Setipiprant,2-(2-(1-naphthoyl)-8-fluoro-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)acetic acid

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 866460-33-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₂₄H₁₉FN₂O₃

Molecular Weight: 402.43

Cell-Permeable?:

Purity: ≥98% by HPLC

Solubilities: >30 mg/ml

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: Apotent and selective CRTh2 antagonist

MDL Number: N/A

PubChem CID: 49843471

SMILES: C1CN(CC2=C1N(C3=C2C=C(C=C3)F)CC(=O)O)C(=O)C4=CC=CC5=CC=CC=C54

InChi: InChI=1S/C24H19FN2O3/c25-16-8-9-21-19(12-16)20-13-26(11-10-22(20)27(21)14-23(28)29)24(30)18-7-3-5-15-4-1-2-6-17(15)18/h1-9,12H,10-11,13-14H2,(H,28,29)

InChi Key: IHAXLPDVOWLUOS-UHFFFAOYSA-N