ACTC1 Antibody | 22-274

ACTC1 Antibody | 22-274 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: A synthetic peptide of human ACTC1

Research Area: Cell Cycle, Signal Transduction

Tested Application: WB, IHC, IF

Application: WB: 1:500 - 1:1000
IHC: 1:10 - 1:50
IF: 1:10 - 1:50

Specificiy: N/A

Positive Control 1: Mouse skeletal muscle

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 42kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, pH7.3.

Concentration: N/A

Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.

Alternate Name: ACTC, Actin, alpha cardiac muscle 1, Alpha-cardiac actinACTC, ASD5, CMD1R, CMH11, LVNC4

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC) .