Actin Antibody (alpha)| F40313-0.08ML

Actin Antibody (alpha)| F40313-0.08ML | Gentaur UK, US & Europe Distribution

Background: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with a-actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an a-actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Format: Purified

Clone: 337CT30.10.1

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Isotype: Mouse IgG1, k

Species Reactivity: Human

Predicted Spacies Reactivity: Bovine, Chicken, Mouse, Pig, Rabbit, Rat

Application: WB, IHC, FACS, ELISA

Application Details: Western blot: 1:100-1:500, IHC (Paraffin): 1:10-1:50, Flow Cytometry: 1:10-1:50

Application Note: Titration of the skeletal muscle Actin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This skeletal muscle Actin antibody is available for research use only.

Purity: Purified

Immunogen: This skeletal muscle Actin antibody was produced from a mouse immunized with ACTA1 recombinant protein.

Storage: Aliquot the skeletal muscle Actin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A