Actinin α polyclonal Antibody | BS90023

Actinin α polyclonal Antibody | BS90023 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB ICC IHC FC

Application Range: WB:1:500-1:1,000 ICC:1:50-1:100 IHC:1:50-1:200 FC:1:50-1:100

Background: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: Actinin α polyclonal Antibody detects endogenous levels of Actinin α protein.

Molecular Weight: 103 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ACTN1, actinin 1 smooth muscle, Actinin alpha 1, actinin, alpha 1, ACTN 1, Actn1, ACTN1, Alpha Actinin 1, Alpha actinin cytoskeletal isoform, Alpha-actinin cytoskeletal isoform, Alpha-actinin-1, BDPLT15, F actin cross linking protein, F-actin cross-linking protein, FLJ40884, FLJ54432, Non muscle alpha actinin 1, Non-muscle alpha-actinin-1,

Immunogen: Recombinant protein within human alpha Actinin aa 350-650.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein affinity purified.

Pathway: