Active LAMP2/CD107b, Human Recombinant | P1740

Active LAMP2/CD107b, Human Recombinant | P1740

Description: LAMP2 (CD107b) is a membrane glycoprotein that functions in the protection, maintenance, and adhesion of the lysosome. LAMP2 plays an important role in chaperone-mediated autophagy to mediate lysosomal degradation of proteins in response to stress. LAMP2 may also have a role in tumor cell metastasis.

Biomolecule/Target:

Synonyms: Lysosomal Associated Membrane Protein 2; Lysosome-Associated Membrane Glycoprotein 2; CD107 Antigen-Like Family Member B; LAMP-2; LGP-96; LGP110; LAMPB; DND

Alternates names:

Taglines: Plays a role in lysosomal protein degradation

NCBI Gene ID #: 3920

NCBI Gene Symbol: Human

Accession #: P13473

Recombinant: True

Source: Human cells

Purity by SDS-PAGE: > 95% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Activity (Specifications/test method):

Biological activity: Immobilized human Galectin-3 (at 1.5 μg/ml, 100 μl/well) can bind Active LAMP2/CD107b with an ED50 of 12.73 μg/ml

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 33.9 kDa (predicted); 78 kDa (observed)

Concentration:

Appearance: Lyophilized protein

Physical form description:

Reconstitution Instructions:

Amino acid sequence: Leu 29 to Ile 375 with C-terminal 6xHis Tag

Handling: Centrifuge the vial prior to opening.

Usage: