Active SLAMF6/Ly108, Human Recombinant | P1738

Active SLAMF6/Ly108, Human Recombinant | P1738

Description: SLAMF6 (also known as Ly108) is a transmembrane protein expressed on natural killer (NK), T-, and B-lymphocytes. SLAMF6 undergoes tyrosine phosphorylation and associates with SH2 domain-containing proteins to function as a coreceptor in NK cell activation. SLAMF6 also has functions in T-cell differentiation and in the humoral immune response.

Biomolecule/Target:

Synonyms: SLAM Family Member 6; NTB-A; KALI; CD352

Alternates names:

Taglines: Key protein in the activation and regulation of natural killer cells

NCBI Gene ID #: 114836

NCBI Gene Symbol: Human

Accession #: Q96DU3

Recombinant: True

Source: Human cells

Purity by SDS-PAGE: > 95% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Activity (Specifications/test method):

Biological activity: Measured by its ability to induce IFN-γ secretion by PBMC cells

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 23.4 kDa (predicted); 30-50 kDa (observed)

Concentration:

Appearance: Lyophilized protein

Physical form description: Lyophilized powder

Reconstitution Instructions:

Amino acid sequence: Leu 28 to Lys 225 with C-terminal His Tag

Handling: Centrifuge the vial prior to opening.

Usage: