Active Syndecan-2/SDC2, Human Recombinant | P1739

Active Syndecan-2/SDC2, Human Recombinant | P1739

Description: Syndecan-2 (SDC2) is a transmembrane heparan saulfate proteoglycan that mediates cell binding, cell signaling, and cytoskeletal organization. SDC2 functions in cell proliferation, cell migration, and cell-matrix interactions. Aberrant SDC2 expression has been observed in several tumor types.

Biomolecule/Target:

Synonyms: Fibroglycan; SYND2; Heparan Sulfate Proteoglycan 1, Cell Surface-Associated; CD362; HSPG1

Alternates names:

Taglines: Mediates cell binding, cell signaling, and cytoskeletal organization

NCBI Gene ID #: 6383

NCBI Gene Symbol: Human

Accession #: P34741

Recombinant: True

Source: Human cells

Purity by SDS-PAGE: > 95% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Activity (Specifications/test method):

Biological activity: Immobilized human basic FGF at 2 μg/ml(100 μl/well) binds Active Syndecan-2/SDC2 with ED50 of 645 ng/ml

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 15.0 kDa (predicted); 32 kDa (observed)

Concentration:

Appearance: Lyophilized protein

Physical form description: Lyophilized powder

Reconstitution Instructions:

Amino acid sequence: Glu 19 to Glu 144 with C-terminal 6xHis Tag

Handling: Centrifuge the vial prior to opening.

Usage: