ACTR3B Antibody (C-term) [APR14804G]

ACTR3B Antibody (C-term) [APR14804G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This ACTR3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-352 amino acids from the C-terminal region of human ACTR3B.

Cellular Localisation: Cytoplasm, cytoskeleton. Cell projection

Molecular Weight: 47608

Clone: Polyclonal

Gene Name: ACTR3B

Gene ID: 57180

Function: Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors.

Summary: Tissue Location: Detected in fetal brain. Detected throughout the adult brain, in neurons from gray matter, but not in white matter Detected in liver, skeletal muscle and pancreas. Detected in lung adenocarcinoma cells with low metastatic potential, but not in lung adenocarcinoma cells with high metastatic potential

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Actin-related protein 3B, ARP3-beta, Actin-like protein 3B, Actin-related protein ARP4, ACTR3B, ARP11, ARP4