ACY-1 polyclonal Antibody | BS90027

ACY-1 polyclonal Antibody | BS90027 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IHC

Application Range: WB:1:2,000-1:10,000 ICC:1:50-1:200 IHC:1:50-1:200

Background: This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene.

Storage & Stability: Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

Specificity: ACY-1 polyclonal Antibody detects endogenous levels of ACY-1 protein.

Molecular Weight: 46 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ACY-1, ACY1, ACY 1, ACY-1, Acy1, ACY1, ACY1D, ACYLASE, Acylase I, Aminoacylase 1, Aminoacylase-1, EC 3.5.1.14, epididymis secretory protein Li 5, HEL-S-5, N acyl L amino acid amidohydrolase, N-acyl-L-amino-acid amidohydrolase, OTTHUMP00000212459, OTTHUMP00000212462, OTTHUMP00000212463, OTTHUMP00000212464, OTTHUMP00000212465 Antibody

Immunogen: Recombinant protein within Human ACY-1 aa 50-250.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein affinity purified.

Pathway: