ADAMTS1 (Human) ELISA Kit | E5110-100

ADAMTS1 (Human) ELISA Kit | E5110-100

Description: ADAMTS1, a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family which plays an important role in various biological and pathological processes, such as development, angiogenesis, inflammation, cancer, arthritis, and atherosclerosis. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. It contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. ADAMTS1 has angiogenic inhibitor activity. It may be associated with various inflammatory processes as well as development of cancer cachexia. It also plays a critical role in follicular rupture. Elevated ADAMTS1 promotes pro-tumorigenic changes such as increased tumor cell proliferation, inhibited apoptosis and altered vascularization. ADAMTS1 functions in the regulation of lymph-angiogenesis and the therapeutic potential of ADAMTS1 in cancer therapy. ’s ADAMTS1 (Human) ELISA Kit is used for the quantitative detection of ADAMTS1 in serum, plasma, tissue homogenates and other biological fluids. It is based on the principle of sandwich ELISA. The capture antibody is pre-coated on 96-well plates. The standards, test samples and biotin conjugated detection antibody are added to the wells subsequently, and washed with wash buffer. HRP-Streptavidin is added and unbound conjugates are washed away with wash buffer. The HRP enzymatic reaction is detected using TMB-substrate. Finally, an acidic stop solution terminates the enzymatic reaction. The color developed is directly proportional to the amount of ADAMTS1 in the sample.

Alternate Name: ADAMTS1 ELISA Kit; METH1 ELISA Kit; a disintegrin-like and metalloprotease ELISA Kit; reprolysin type with thrombospondin type 1 motif ELISA Kit; ADAM metallopeptidase with thrombospondin type 1 motif ELISA Kit; ADAMTS 1 ELISA Kit; ADAM-TS1 ELISA Kit; ADAMTS-1 ELISA Kit

Tag Line: A highlsensitive sandwich ELISA kit for the quantitative measurement of ADAMTS1

Summary: N/A

Detection Method: Absorbance is measured at 450 nm

Sample Type: Human Serum, Plasma, Tissue lysates and other biological fluids

Species Reactivity: Human

Applications: The ELISA kit is used for the quantitative detection of ADAMTS1 in serum, plasma, tissue homogenates and other biological fluids

Features & Benefits: Detection range: 0.781-50 ng/ml Recovery Rate: 89-103% for serum, 86-105% for EDTA plasma and 87-103% for heparin plasma Sensitivity: 0.469 ng/ml Highly sensitive and specific Assay Precision; Intra-Assay CV < 8% and Inter-Assay < 10%