ADAMTS15 Antibody (N-Term) [APR33185G]

ADAMTS15 Antibody (N-Term) [APR33185G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ADAMTS15 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 29-59 amino acids from the region of human ADAMTS15.

Cellular Localisation: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P59384}. Cell surface {ECO:0000250|UniProtKB:P59384}

Molecular Weight: 103287

Clone: Polyclonal

Gene Name: ADAMTS15

Gene ID: 170689

Function: Metalloprotease which has proteolytic activity against the proteoglycan VCAN, cleaving it at the 'Glu-1428-|-1429-Ala' site. Cleaves VCAN in the pericellular matrix surrounding myoblasts, facilitating myoblast contact and fusion which is required for skeletal muscle development and regeneration.

Summary: Tissue Location: Expressed in fetal liver and kidney, but not in any of the adult tissues examined.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 15, ADAM-TS 15, ADAM-TS15, ADAMTS-15, 3424-, ADAMTS15