ADAMTS17 polyclonal Antibody | BS61126

ADAMTS17 polyclonal Antibody | BS61126 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB: 1:500~1:1000

Background: ADAMTS (a disintegrin and metalloproteinase domain with Thrombospondin type-1 modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions, including arthritis and cancer. ADAMTS protein family members contain an N-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain and a C-terminus that contains a varying number of Thrombospondin type-1 (TSP-1) motifs. ADAMTS-17 (ADAM metallopeptidase with Thrombospondin type-1 motif, 17) is a 1,095 amino acid secreted protein that belongs to the ADAMTS family. Expressed in liver, prostate, brain and in fetal lung, ADAMTS-17 has seven N-glycosylation sites and shares 56% sequence identity with a related family member, ADAMTS-19. ADAMTS-17 has a conserved cysteine residue in its cysteine-switch motif that, when bound to one zinc ion, inhibits the enzymatic activity of the protein.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ADAMTS17 polyclonal Antibody detects endogenous levels of ADAMTS17 protein.

Molecular Weight: ~ 121 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: A disintegrin and metalloproteinase with thrombospondin motifs 17; ADAM-TS 17; ADAM-TS17; ADAMTS-17; ADAMTS17

Immunogen: Synthetic peptide, corresponding to Human ADAMTS17.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: