ADAMTS6 (Human) ELISA Kit | E5111-100

ADAMTS6 (Human) ELISA Kit | E5111-100

Description: ADAMTS6 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family which plays an important role in various biological and pathological processes, such as development, angiogenesis, inflammation, cancer, arthritis, and atherosclerosis. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. Enhanced ADAMTS6 expression suppressed cell migration, invasion, and tumorigenesis, whereas knockdown promoted these characteristics. The extracellular signal-regulated kinase (ERK) pathway was partially involved in ADAMTS6-mediated inhibition of BC development, and miR-221-3p was identified as a predicted target for ADAMTS6. ADAMTS6 is a potential prognostic biomarker for Breast cancer. ’s ADAMTS6 (Human) ELISA Kit is used for the quantitative detection of ADAMTS6 in serum, plasma, tissue homogenates and other biological fluids. Its based on the principle of sandwich ELISA. The capture antibody is pre-coated on 96-well plates. The standards, test samples and biotin conjugated detection antibody are added to the wells subsequently, and washed with wash buffer. HRP-Streptavidin is added and unbound conjugates are washed away with wash buffer. The HRP enzymatic reaction is detected using TMB-substrate. Finally, an acidic stop solution terminates the enzymatic reaction. The color developed is directly proportional to the amount of ADAMTS6 in the sample.

Alternate Name: ADAMTS6 ELISA Kit; A disintegrin and metalloproteinase with thrombospondin motifs 6 ELISA Kit; ADAM-TS 6 ELISA Kit; ADAM-TS6 ELISA Kit; ADAMTS-6 ELISA Kit

Tag Line: A highly sensitive sandwich ELISA kit for the quantitative measurement of ADAMTS6

Summary: N/A

Detection Method: Absorbance is measured at 450 nm

Sample Type: Human Serum, Plasma, Tissue lysates and other biological fluids

Species Reactivity: Human

Applications: The ELISA kit is used for the quantitative detection of ADAMTS6 in serum, plasma, tissue homogenates and other biological fluids

Features & Benefits: Detection range: 31.25-2000 pg/ml Highly sensitive and specific Recovery Rate: 86104% for serum, 87-99% for EDTA plasma and 86-103% for heparin plasma Sensitivity: 18.75 pg/ml Assay Precision; Intra-Assay CV < 8% and Inter-Assay < 10%