ADD1 Polyclonal Antibody | E-AB-10034

ADD1 Polyclonal Antibody | E-AB-10034 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ADD A, ADD1, ADDA, ADDA, Adducin 1 (alpha), Alpha adducin, Alpha-adducin, Erythrocyte adducin alpha subunit, Erythrocyte adducin subunit alpha, MGC3339, MGC44427, OTTHUMP00000151163, OTTHUMP00000151164, OTTHUMP00000151165, OTTHUMP00000218664, OTTHUMP00000218665

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal Transduction, Tags and Cell Markers

Background: Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human ADD1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A