Description
ADFP polyclonal Antibody | BS8094 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Background: Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase to endosomes from the Golgi and back again. Cargo selection protein TIP47, also designated placental protein 17, is required for the transport from endosomes to the trans-Golgi network and interacts with the cytoplasmic domains of both cation-dependent and cation-independent MPRs. Another member of the peripilin family, Adipophilin (ADRP), is a protein associated with the globule surface membrane material of milk lipid globules. The phos-phoprotein Perilipin (Peri) is located on the surface of intracellular lipid droplets within adipocytes where it protects lipid storage droplets by coating them in adipocytes until they are digested by lipase. As a critical regulator of lipolysis, elevated Perilipin levels have been linked to obesity.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ADFP polyclonal Antibody detects endogenous levels of ADFP protein.
Molecular Weight: ~ 48 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Perilipin-2; Adipophilin; Adipose differentiation-related protein; ADRP; PLIN2; ADFP
Immunogen: Recombinant full length Human ADFP.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Phosphoinosotode Signaling,Protein Kinase C Signaling,Regulation of Actin Dynamics,Warburg Effect,Regulation of Microtubule Dynamics,SAPK JNK Signaling Cascades,Inhibition of Apoptosis,G Protein-coupled Receptors Signaling to MAPK Erk,Mitochondrial Control of Apoptosis,