Adipophilin, human, recombinant | 4597

Adipophilin is a 49 kDa protein that belongs to the PAT family (perilipin, adipophilin, TIP47, S3-12 and OXPAT), which comprises proteins involved in the coating of lipid droplets. ADFP is expressed in lipid droplets of vitamin A-storing hepatic stellate cells and additionally in lipid droplets of steatotic hepatocytes. ADFP expression has a role in clear cell renal carcinoma differentiation. Most recently, it has been discovered that patients with kidney cancers had high levels of ADFP in their urine, suggesting that ADFP could be an excellent marker for kidney cancer.

4597 | Adipophilin human recombinant DataSheet

Biomolecule/Target: Adipophilin

Synonyms: Adipose differentiation-related protein, ADRP, ADFP, MGC10598.

Alternates names: Adipose differentiation-related protein, ADRP, ADFP, MGC10598, Perilipin-2

Taglines: A major constituent of the globule surface

NCBI Gene ID #: 493806

NCBI Gene Symbol: SDF1

Gene Source: Human

Accession #: O62657

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 97%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: The activity is determined by its ability to chemoattract human T cells at 10 - 75 ng/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 8.5 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized from 0.5 mg/ml solution containing 20mM Tris pH 7.5, and 20 mM NaCl,

Reconstitution Instructions: Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions.

Amino acid sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRF KM