ADIPOR2 Antibody (Center) [APR32129G]

ADIPOR2 Antibody (Center) [APR32129G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ADIPOR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-72 amino acids from the Central region of human ADIPOR2.

Cellular Localisation: Cell membrane; Multi-pass membrane protein Note=Localized to the cell membrane and intracellular organelles

Molecular Weight: 43884

Clone: Polyclonal

Gene Name: ADIPOR2 (HGNC:24041)

Gene ID: 79602

Function: Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295) . Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels (By similarity) .

Summary: Tissue Location: Ubiquitous (PubMed:16044242) . Highly expressed in skeletal muscle, liver and placenta (PubMed:12802337) . Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung (PubMed:12802337)

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IF, FC

Dilution: WB--1:1000

Synonyms: Adiponectin receptor protein 2, Progestin and adipoQ receptor family member II, ADIPOR2, PAQR2