ADM polyclonal Antibody | BS61561

ADM polyclonal Antibody | BS61561 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and the maintenance of cardiovascular functioning, and in hypertensive patients, the level of ADM in plasma is upregulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions and ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and this peptide can exert central effects such as decreasing food ingestion.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ADM polyclonal Antibody detects endogenous levels of ADM protein.

Molecular Weight: ~ 25 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ADM; AM; ProAM N-terminal 20 peptide; PAMP; ProAM-N2

Immunogen: Synthetic peptide, corresponding to amino acids 116-160 of Human ADM

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Pathway: