ADSL (Adenylosuccinate Lyase) monoclonal Antibody | MB62056

ADSL (Adenylosuccinate Lyase) monoclonal Antibody | MB62056 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Mouse, Rat, Dog

Application: FC, IHC, WB

Application Range: WB 1:500~2000, IHC 1:150, FLOW 1:100

Background: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and, in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: adenylosuccinate lyase

Molecular Weight: 54.7 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: AMPS; ASASE; ASL

Immunogen: Full length human recombinant protein of human ADSL (NP_000017) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A