AEBP2 polyclonal Antibody | BS70801

AEBP2 polyclonal Antibody | BS70801 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Background: Adipocyte enhancer-binding protein 2 (AEBP2), also known as zinc finger protein AEBP2, is an 817 amino acid member of the AEBP2 C2H2-type zinc-finger protein family. Localized to the nucleus, AEBP2 acts as a DNA-binding transcriptional repressor of the adipose P2 (aP2) gene. The aP2 gene, which encodes the adipose fatty acid-binding protein, plays a critical role in triglyceride metabolism during adipocyte differentiation. The AE-1 region in the proximal promoter region of the aP2 gene functions as either a positive or negative regulatory element. C/EBPå binds to the AE-1 sequence and functions as a transcriptional activator of aP2, whereas other proteins, such as AEBP2, bind to the region and repress gene expression.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: AEBP2 polyclonal Antibody detects endogenous levels of AEBP2 protein.

Molecular Weight: ~ 54 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: AE-binding protein 2; Zinc finger protein AEBP2

Immunogen: Recombinant protein of human AEBP2.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A