AF/LE Purified Anti-Human CD20 Antibody[2H7] | E-AB-F12120

AF/LE Purified Anti-Human CD20 Antibody[2H7] | E-AB-F12120 | Gentaur UK, US & Europe Distribution

Category: Flow Cytometry Antibody

Synonyms: Bp35,Leukocyte surface antigen Leu-16,MS4A1,B-lymphocyte surface antigen B1

Swissprot Code: P11836

Application: Depletion, FCM, IHC, IP

Reactivity: Human

Host: Mouse

Isotype: Mouse IgG2b, κ

Reaserch Area: Cancer, Immunology, Stem cells

Background: CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C. Do not freeze.

Immunogen: N/A

Purification Method: N/A

Dilution: N/A

Clone: 2H7

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)