AF/LE Purified Anti-Human CD28 Antibody[CD28.2] | E-AB-F11950

AF/LE Purified Anti-Human CD28 Antibody[CD28.2] | E-AB-F11950 | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: PAS2,MNS,HGpMiX,GYPA,GPSAT

Swissprot Code: P10747

Application: Activ, FCM, IHC, IP

Reactivity: Mouse

Host: Rat

Isotype: Rat IgG1, κ

Research Areas: Cancer, Immunology, Stem cells

Backgroun: CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C. Do not freeze.

Immunogen: N/A

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Purification Method: N/A

Dilution: N/A

Clone: CD28.2

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A