AF/LE Purified Anti-Human CD40 Monoclonal Antibody | DL22251F

AF/LE Purified Anti-Human CD40 Monoclonal Antibody | DL22251F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: Bp50, CDw40, CD40L receptor, TNFRSF5

Reactivity: Human

Application: Stim, FA, FCM

Background: CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand) .

Concentration: 0.2 mg/mL

Conjugation: None (Purified antibody, Azide Free/Low endotoxin)

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.

Clone: G28.5

Isotype: Mouse IgG1, κ