AF/LE Purified Anti-Human/Monkey CD154 Monoclonal Antibody | DL21618F

AF/LE Purified Anti-Human/Monkey CD154 Monoclonal Antibody | DL21618F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: CD40L, gp39, TRAP, T-BAM, TNFSF5

Reactivity: Human, Monkey

Application: Block, FCM, IP

Background: CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.

Concentration: 0.2 mg/mL

Conjugation: None (Purified antibody, Azide Free/Low endotoxin)

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.

Clone: 5C8

Isotype: Mouse IgG2a, κ