AF/LE Purified Anti-Human/Mouse IL-5 Monoclonal Antibody | DL22189F

AF/LE Purified Anti-Human/Mouse IL-5 Monoclonal Antibody | DL22189F | Gentaur UK, US & Europe Distribution

Host: Rat

Synonyms: Interleukin-5, IL-5, B-cell differentiation factor I, T-cell replacing factor, TRF

Reactivity: Human, Mouse

Application: Depletion, Neut, ICFCM, WB, IHC

Background: IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.

Concentration: 0.2 mg/mL

Conjugation: None (Purified antibody, Azide Free/Low endotoxin)

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.

Clone: TRFK5

Isotype: Rat IgG1, κ