AF/LE Purified Anti-Human/Mouse/Rat CD47 Antibody[MIAP410] | E-AB-F10160

AF/LE Purified Anti-Human/Mouse/Rat CD47 Antibody[MIAP410] | E-AB-F10160 | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP

Swissprot Code: Q08722,Q61735,P97829

Application: FCM,WB,IH,IP,ICC&IF

Reactivity: Mouse

Host: Armenian Hamster

Isotype: Armenian Hamster IgG

Research Areas: Cancer, Immunology

Backgroun: CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C. Do not freeze.

Immunogen: N/A

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Purification Method: N/A

Dilution: N/A

Clone: MIAP410

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A