AF/LE Purified Anti-Mouse CD120b Antibody[TR75-54.7] | E-AB-F10350

AF/LE Purified Anti-Mouse CD120b Antibody[TR75-54.7] | E-AB-F10350 | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: Tumor necrosis factor receptor superfamily member 1B,Tnfrsf1b,Tumor necrosis factor receptor 2,TNF-R2,TNF-RII,TNFR-II,p75,p80 TNF-alpha receptor,CD120b

Swissprot Code: P25119

Application: FCM,WB,Block,IP

Reactivity: Human

Host: Mouse

Isotype: Mouse IgG1, κ

Research Areas: Cell Biology,Immunology,Signal Transduction,Cancer,Cardiovascular,Neuroscience

Backgroun: CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C. Do not freeze.

Immunogen: N/A

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Purification Method: N/A

Dilution: N/A

Clone: TR75-54.7

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A