AF/LE Purified Anti-Mouse CD161/NK1.1 Monoclonal Antibody | DL20024F

AF/LE Purified Anti-Mouse CD161/NK1.1 Monoclonal Antibody | DL20024F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: Killer cell lectin-like receptor subfamily B member 1C, Klrb1c, CD161 antigen-like family member C, Ly-55c, CD161/NK1.1, NKR-P1.9, NKR-P1C, NKR-P1 40, CD161c

Reactivity: Mouse

Application: Activ, Block, Depletion, FCM, IHC, IF

Background: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

Concentration: 0.2 mg/mL

Conjugation: None (Purified antibody, Azide Free/Low endotoxin)

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.

Clone: PK136

Isotype: Mouse IgG2a, κ