AF/LE Purified Anti-Mouse CD209b Antibody[22D1] | E-AB-F10220

AF/LE Purified Anti-Mouse CD209b Antibody[22D1] | E-AB-F10220 | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: CD209 antigen-like protein B,Cd209b,DC-SIGN-related protein 1,DC-SIGNR1,OtB7,CD209,Cd209b

Swissprot Code: Q8CJ91

Application: FCM,IHC-F,WB

Reactivity: Mouse

Host: Hamster

Isotype: Syrian Hamster IgG

Research Areas: Immunology,Cardiovascular

Backgroun: CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C. Do not freeze.

Immunogen: N/A

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Purification Method: N/A

Dilution: N/A

Clone: 22D1

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A