AF/LE Purified Anti-Mouse CD38 Monoclonal Antibody | DL22118F

AF/LE Purified Anti-Mouse CD38 Monoclonal Antibody | DL22118F | Gentaur UK, US & Europe Distribution

Host: Rat

Synonyms: ADP-ribosyl cyclase 1, ADPRC 1, CD38, NIM-R5 antigen，2'-phospho-cyclic-ADP-ribose transferase

Reactivity: Mouse

Application: Activ, Stim, FCM, ELISA, IHC, IF

Background: CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

Concentration: 0.2 mg/mL

Conjugation: None (Purified antibody, Azide Free/Low endotoxin)

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.

Clone: NIMR5

Isotype: Rat IgG2a, κ