AF/LE Purified Anti-Mouse CD80 Antibody[16-10A1] | E-AB-F09920

AF/LE Purified Anti-Mouse CD80 Antibody[16-10A1] | E-AB-F09920 | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: T-lymphocyte activation antigen CD80,Cd80,Activation B7-1 antigen,B7

Swissprot Code: Q00609

Application: Block, FCM

Reactivity: Mouse

Host: Rat

Isotype: Rat IgG2a, κ

Research Areas: Cancer, Immunology, Stem cells

Backgroun: CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C. Do not freeze.

Immunogen: N/A

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Purification Method: N/A

Dilution: N/A

Clone: 16-10A1

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A