Description
AF/LE Purified Anti-Mouse F4/80 Antibody[CI:A3-1] | E-AB-F09950 | Gentaur UK, US & Europe Distribution
Category: Flowcytometry Antibody
Synonyms: Adhesion G protein-coupled receptor E1,Adgre1,Cell surface glycoprotein F4/80,EGF-like module receptor 1,Adgre1,Emr1, Gpf480
Swissprot Code: Q61549
Application: Depletion, FA, FCM, WB, IHC
Reactivity: Mouse
Host: Rat
Isotype: Rat IgG2b, κ
Research Areas: Immunology,Tags & Cell Markers
Backgroun: F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.
Concentration: 0.5 mg/mL
Storage: Store at 2~8°C. Do not freeze.
Immunogen: N/A
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Purification Method: N/A
Dilution: N/A
Clone: CI:A3-1
Conjugation: None (Purified antibody-Azide Free/Low endotoxin)
Moleculair Weight(Calculated): N/A
Moleculair Weight(Observed): N/A