AF488 Anti-Human CD127/IL-7RA Antibody[A019D5] | E-AB-F1152L

AF488 Anti-Human CD127/IL-7RA Antibody[A019D5] | E-AB-F1152L | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: Interleukin-7 receptor subunit alpha,IL-7RA,CDw127,CD127,IL-7Rα

Swissprot Code: P16871

Application: FCM

Reactivity: Human

Host: Mouse

Isotype: Mouse IgG2b, κ

Research Areas: Cancer, Immunology, Stem cells

Backgroun: CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

Concentration: N/A

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: A019D5

Conjugation: AF488

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A