AF488 Anti-Human CD161 Antibody[HP-3G10] | E-AB-F1155L

AF488 Anti-Human CD161 Antibody[HP-3G10] | E-AB-F1155L | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: CLEC5B, NKRP1A,NKR-P1A,HNKR-P1a,KLRB1

Swissprot Code: Q12918

Application: FCM

Reactivity: Human

Host: Mouse

Isotype: Mouse IgG2a, κ

Research Areas: Immunology

Backgroun: CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.

Concentration: N/A

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: HP-3G10

Conjugation: AF488

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A