AF488 Anti-Human CD57 Antibody[HNK-1] | E-AB-F1067L

AF488 Anti-Human CD57 Antibody[HNK-1] | E-AB-F1067L | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1,B3GAT1,GlcAT-P,GlcUAT-P,GLCATP

Swissprot Code: Q9P2W7

Application: FCM

Reactivity: Human

Host: Mouse

Isotype: Mouse IgG2b, κ

Research Areas: Cancer, Immunology

Backgroun: CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).

Concentration: N/A

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: HNK-1

Conjugation: AF488

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A